Interferon Regulatory Factor 1 in Mycobacterial Infection
نویسندگان
چکیده
منابع مشابه
IRF 1 ( interferon regulatory factor 1 )
Hugo: IRF1 Other names: IRF-1; MAR Location: 5q23.3 Note: Interferon regulatory factor 1 belongs to a family of transcription factors described for their role in regulating type I and type II interferons. Specifically, IRF1 has been identified as an activator of interferon alpha and beta transcription. Furthermore, it has been shown to play a role in the regulation of tumour suppression. IRF1 l...
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Author affiliations: Hospices Civils de Lyon, International Center for Research in Infectiology, Université Claude Bernard Lyon 1, INSERM U1111, Lyon, France (F. Valour, T. Perpoint, A. Sénéchal, T. Ferry, C. Chidiac, F. Ader); Necker-Enfants Malades Hospital, INSERM, Paris Descartes University, Paris, France (J. Bustamante); St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockef...
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Interferon regulatory factor (IRF) family members, especially interferon regulatory factor-1 (IRF-1) and interferon regulatory factor-8 (IRF-8 or ICSBP), play important roles in interferon signaling in a wide range of host responses to infection and tumor growth. Interleukin-27 (IL-27), as a member of the IL-12 cytokine family, not only acts as a proinflammatory cytokine that regulates the diff...
متن کاملIRF4 (interferon regulatory factor 4)
Other names: IRF-4; NF-EM5; LSIRF (lymphocytespecific interferon regulatory factor); MUM1 (multiple myeloma oncogene 1) HGNC (Hugo): IRF4 Location: 6p25.3 Local order: IRF4 is located on chromosome 6 at the telomeric extremity of the short arm, and lies between the DUSP22 (dual specificity phosphatase 22) and EXOC2 (exocyst complex component 2) genes. Note: IRF4 belongs to the IRF (interferon r...
متن کاملEctopic expression of interferon regulatory factor-1 potentiates granulocytic differentiation.
Numerous transcription factors allow haematopoietic cells to respond to lineage- and stage-specific cytokines and to act as their effectors. It is increasingly evident that the interferon regulatory factor-1 (IRF-1) transcription factor can selectively regulate different sets of genes depending on the cell type and/or the nature of cellular stimuli, evoking distinct responses in each. In the pr...
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ژورنال
عنوان ژورنال: Microbiology and Immunology
سال: 2002
ISSN: 0385-5600
DOI: 10.1111/j.1348-0421.2002.tb02760.x